The following information is a summary about Renova. It is not intended to replace a doctor's instructions.

(TRETINOIN CREAM)

USES
Renova is used to improve the appearance of the skin by reducing fine lines and wrinkles, reducing roughness and improving coloration. It can also be used to treat acne.

HOW TO USE THIS MEDICATION
This medication is for use on the face as directed, usually once a day at bedtime. Apply a pea-size amount of cream to clean, dry skin on the face being careful to avoid the eyes, nostrils and mouth. Cover affected area lightly. Wash hands after use. Do not use Renova more often than prescribed or in large amounts. It will not give you faster or better results but will increase the risk of side effects. Do not use on sunburn or eczema or other serious skin conditions. Effects of this medication will be gradual with most improvement seen in the first 6 months of continued therapy. If used for acne the condition may worsen at first, then improve.

PRECAUTIONS
Before taking Renova tell your doctor if you have any pre-existing skin disorders or if you have any allergies. This medication increases your sensitivity to the sun so limit exposure and avoid sun lamps. Use a sunscreen and wear protective clothing when outdoors. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is unknown if this drug is excreted into breast milk so consult with your doctor before breast-feeding.

SIDE EFFECTS
You may experience mild redness or stinging, itching, burning, skin scaling, peeling and dry skin the first several weeks as your body adjusts to the medication. If any of these effects continue or become severe, discontinue use and notify your doctor.

MISSED DOSE
If you miss a dose, use it as soon as remembered; do not use if it is almost time for the next dose. Instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

DRUG INTERACTIONS
Tell your doctor of any nonprescription or prescription medication you may take including isotretinoin, amiodarone, tetracycline or quinolone antibiotics, sulfa-drugs or phenothiazines as they increase skin sensitivity to the sun. Also minoxidil and any skin medication, soaps, cleansers, cosmetics, astringents or any facial products that may be drying or irritating (e.g., alcohol-containing facial products. Benzoyl peroxide should not be applied at the same time as this medication.

NOTES
Renova is not a cosmetic. It is to be used in conjunction with a comprehensive skin care and sun avoidance program.

STORAGE
Store this medication at room temperature between 59 and 86 degrees F (15 and 25 degrees C). Do not freeze. KEEP THIS AND ALL MEDICATIONS OUT OF THE REACH OF CHILDREN.