The following information is a summary about Tenuate and also Generic Tenuate (Diethylpropion). It is not intended to replace a doctor's instructions.

(Appetite Suppressant - ORAL)

USES
Tenuate, an appetite suppressant, is prescribed for short-term use (a few weeks) as part of an overall diet plan for weight reduction. It is available in two forms: immediate-release tablets (Tenuate) and controlled-release tablets (Tenuate Dospan). Tenuate should be used with a behavior modification program.

HOW TO TAKE THIS MEDICATION
This medication is to be taken once daily, swallowed whole, in midmorning. Do not increase your dose or take it more often than prescribed because this drug can be habit forming. Also, if used for a longer period of time, do not suddenly stop this medication without first consulting your doctor. Tenuate is usually taken for 8 to 12 weeks.

SIDE EFFECTS
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue using Tenuate. Side effects may include: abdominal discomfort, abnormal redness of the skin, anxiety, blood pressure elevation, blurred vision, breast development in males, bruising, changes in sex drive, chest pain, constipation, depression, diarrhea, difficulty with voluntary movements, dizziness, drowsiness, dryness of the mouth, feelings of discomfort, feelings of elation, feeling of illness, hair loss, headache, hives, impotence, inability to fall or stay asleep, increased heart rate, increased seizures in epileptics, increased sweating, increased volume of diluted urine, irregular heartbeat, jitteriness, menstrual upset, muscle pain, nausea, nervousness, over stimulation, painful urination, palpitations, pupil dilation, rash, restlessness, shortness of breath or labored breathing, stomach and intestinal disturbances, tremors, unpleasant taste, vomiting.

PRECAUTIONS
Tenuate will lose its effectiveness within a few weeks. When this begins to happen, you should discontinue the medicine rather than increase the dosage.

DRUG INTERACTIONS
Tenuate or Tenuate Dospan may interact with alcohol unfavorably. Do not drink alcohol while taking this medication. If Tenuate or Tenuate Dospan are taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important that you consult your doctor before combining Tenuate with the following: blood pressure medications such as Ismelin, Insulin and Phenothiazine drugs such as the major tranquilizer Thorazine.

NOTES
If you are sensitive to or have ever had an allergic reaction to Tenuate or other appetite suppressants, you should not take this medication. Make sure your doctor is aware of any drug reactions you have experienced.

Do not take this drug if you have severe hardening of the arteries, an overactive thyroid, glaucoma, or severe high blood pressure, or if you are agitated, have a history of drug abuse or are taking an MAO inhibitor (antidepressant drug such as Nardil) or have taken one within the last 14 days.

Tenuate or Tenuate Dospan may impair your ability to engage in potentially hazardous activities. Therefore, make sure you know how you react to this medication before you drive, operate dangerous machinery, or do anything else that requires alertness or concentration.

If you have heart disease or high blood pressure, use caution when taking this medication.

This drug may increase convulsions in some epileptics. Your doctor should monitor you carefully if you have epilepsy.

Psychological dependence has occurred while taking this drug. Talk with your doctor if you find you are relying on Tenuate to maintain a state of well-being. The abrupt withdrawal of this medication following prolonged use at high doses may result in extreme fatigue, mental depression, and sleep disturbances.

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek emergency medical treatment immediately.

Symptoms of Tenuate overdose may include: abdominal cramps, assaultiveness, confusion, depression, diarrhea, elevated blood pressure, fatigue, hallucinations, irregular heartbeat, lowered blood pressure, nausea, overreactive reflexes, panic state, rapid breathing, restlessness, tremors, vomiting.

MISSED DOSE
If you are taking the immediate-release form of Tenuate, go back to your regular schedule at the next meal. If you are taking Tenuate Dospan, take the missed dose as soon as you remember. If you do not remember until the next day, skip the dose. NEVER TAKE TWO DOSES AT ONCE.

STORAGE
Store at room temperature in a tightly closed container. Protect from excessive heat